E1 - Episode 1

Aired: January 07, 2020

When a defeated Kian finds himself in a dark place, will Jac be able to pull him back from the edge? Meanwhile, a past acquaintance puts Max in a compromising position.

E2 - Episode 2

Aired: January 14, 2020

Jac and Kian return to work, but can they support each other and conquer their demons? Demoted and back in the trenches, Serena must find a role for herself. And will Sacha’s efforts to help with Essie’s home life only push her into Ben’s arms for good?

E3 - Episode 3

Aired: January 21, 2020

With Jason's job in jeopardy, can Serena afford to put her neck on the line for her nephew? Tracey McKendrick brings trouble to Holby. How far will Nicky go to protect her mum? And can Essie trust boyfriend Ben enough to share the secret of baby Isla’s illegal adoption?

E4 - Episode 4

Aired: January 28, 2020

On Holocaust Memorial Day, Sacha's beloved great-aunt - a Holocaust survivor - is admitted in very poor health. Meanwhile, Cameron sees red while dealing with a stabbing victim.

E5 - Episode 5

Aired: February 04, 2020

It’s the day of Sacha's groundbreaking transplant operation. As he is still overcoming a bereavement, Max wonders whether Sacha is fit to carry out the procedure. Meanwhile, Nicky’s woes escalate when Max finds out that she’s been moonlighting, and Donna has stars in her eyes when she meets a patient who happens to be a casting director.

E6 - Episode 6

Aired: February 11, 2020

It’s Valentine’s Day, but will Cupid’s arrow hit the target for Chloe and Cameron? Will Nicky risk a life to pay off a debt? A troubled Sacha is guided by the faith of an old friend.

E7 - Episode 7

Aired: February 18, 2020

It’s the morning after the night before, but will Cameron and Chloe reconcile? A familiar face waltzes back into Holby and ruffles a few feathers, and when Jac’s plans with Emma fall through, a colourful character comes to the rescue.

E8 - Episode 8

Aired: February 25, 2020

A galvanised Ric clashes with Max as he goes above and beyond for a patient. Essie has to choose between Ben and Sacha, and Kian returns from Canada determined to push Jac out of her comfort zone.

E9 - Episode 9

Aired: February 26, 2020

Max finds herself in a desolate place after receiving distressing news, but following her fallout with Ric has she lost her closest confidante? Jac and Kian must decide who will be Darwin’s next clinical lead, but neither is quite ready to make the call. Essie learns that nothing stays secret for long as shocking revelations threaten her friendship with Dom.

E10 - Episode 10

Aired: March 10, 2020

Xavier unearths a shocking secret, and Fletch struggles to handle the nursing shortage. Reeling from recent revelations, Sacha, Essie, Dom and Ben peform life-saving surgery on a vulnerable child.

E11 - Episode 11

Aired: March 24, 2020

With Xavier hot on his trail, how far will Cameron go to keep Evan dead and buried? Roger Ffolkes forces Ben to own his secrets. Is Ben brave enough to handle the truth? The board scrutinises Jac's team, and she is keen to impress them with a complex and rare surgery that will put the team ahead of the competition. But is everyone ready for a tough day in theatre?

E12 - Episode 12

Aired: March 31, 2020

Max is feeling nervous at the thought of seeing her daughter again after years of estrangement. ED nurse David Hide joins the Darwin crew for the day, but Jac deems him not worthy. Essie waits for her routine cancer check-up, while Sacha encourages her to bury the hatchet with Dom.

E13 - Episode 13

Aired: April 07, 2020

Max struggles to come to terms with an explosive revelation. Jac and Kian bond over pizza and wine, and Dom tries to reason with a distraught Essie.

E14 - Episode 14

Aired: April 14, 2020

As his disciplinary hearing begins, Xav is determined to prove that Cameron killed Evan. Essie faces the fight of her life as she undergoes her first round of chemotherapy.

E15 - Episode 15

Aired: June 02, 2020

Essie’s friends try to keep things normal as she continues her chemotherapy. Jac and Kian’s relationship takes an unexpected turn, and can Guy keep his relationship under wraps?

E16 - Episode 16

Aired: June 09, 2020

Essie puts on a brave face, but the effects of chemo start to take a toll. Guy has a lot to prove as he faces a challenging case on his first day on AAU, and Jac tries to keep things professional with Kian on the ward, but he has other ideas

E17 - Episode 17

Aired: June 16, 2020

As things with Jac heat up, Kian is thrown off balance when a patient causes painful memories to resurface. Tensions run high as Louis adjusts to life in his mum’s hospital, and Guy tries to make amends for last week. Fletch puts his foot in it when he receives an unwanted gift.

E18 - Episode 18

Aired: June 23, 2020

Fletch and his daughter Evie reveal life-changing secrets they have both been keeping, and what will Max do when dangerous truths are exposed on the biggest day of her career?

E19 - Episode 19

Aired: June 30, 2020

Cameron is gutted when his performance review doesn’t go to plan, and Nicky’s attempts to find a life-saving treatment for Brenda put her at odds with Jac. While staff fuss over Fletch as he recovers from surgery, Essie may know something that will change life on Keller forever.

E20 - Episode 20

Aired: July 07, 2020

Nicky is stressed and exhausted, with devastating consequences at work. As she struggles to cope with the pressure from her mother, a tragic incident pushes her over the edge. Ange tells Cameron he is not ready to take the next step in his career. Frustrated by the rejection, he takes out his anger on Louis. Sacha decides to respect Essie's wishes concerning her cancer treatment, but Dominic urges him to persuade her not to give up on palliative care.

E21 - Episode 21

Aired: July 14, 2020

Nicky must confront her fears, Fletch and Essie try to remain upbeat, and Guy is determined to prove he's still a top surgeon.

E22 - Episode 22

Aired: July 21, 2020

Kian returns to Holby, determined to make amends with Jac. Essie searches for answers, and Ric sets out on a personal vendetta.

E23 - Episode 23

Aired: July 28, 2020

Cameron fears new locum Drew is out to expose him, Kian spends the day babysitting Emma in order to win back Jac's heart, and how low will Sacha stoop to convince Essie?

E24 - Episode 24

Aired: August 04, 2020

Ric clashes with Max when his determination to destroy Guy puts his health at risk. Distressed by Frankie’s disappearance, Essie’s suspicions are raised when Sacha avoids the subject. Chloe struggles to keep things professional when her dating life spills onto the ward.

E25 - Episode 25

Aired: August 11, 2020

Finding Ric unconscious in theatre, Guy capitalises on the unexpected opportunity. Sacha tries to make things right with Essie, and Nicky receives a surprising offer.

E26 - Episode 26

Aired: November 10, 2020

Rick wakes up from his coma to find the world is in the middle of a COVID 19 pandemic.

E27 - Episode 27

Aired: November 17, 2020

Jac rushes in a mystery patient, whose arrival sets in motion in a deepening medical crisis that could have serious repercussions for her secret relationship with Kian. Keller is shocked when a new member of staff reveals the truth about Sacha's deception, and is tempted to take out his anguish on a vulnerable patient. Cameron basks in the glory of being declared a hero - prompting Nicky to issue him with an ultimatum.

E28 - Episode 28

Aired: November 24, 2020

Max wrestles with the after-effects of neurosurgery and the financial pressure on the hospital, but things get worse when an encounter with an old enemy puts a strain on her relationship with Louis. Kian brings in some new recruits to help solve Jac's medical mystery, and a new arrival stirs up unpleasant memories for Donna.

E29 - Episode 29

Aired: December 01, 2020

Sacha battles against the odds to keep going after Essie’s death. Cameron tries to win Chloe over, with dramatic consequences. Kian finds himself in a compromised position when Clayton calls him out.

E30 - Episode 30

Aired: December 08, 2020

Chloe and Cameron become completely estranged when she finds out that they are competing for the same job. Sacha and Jodie continue to stick together against the naysayers.

E31 - Episode 31

Aired: December 15, 2020

Kian’s cold turkey is tested when Sarah Jane calls in a favour. Can Kian stand firm, or will he crack under the pressure?

E32 - Episode 32

Aired: January 05, 2021

Sacha buries his head in the sand when Beka is taken ill on New Year’s Eve. Will he figure out the truth before it’s too late? Kian is on edge as Sarah Jane avoids his calls, and his stash is running out. Can he convince Jac he’s fine when she worries that their relationship is the problem? It’s total chaos on AAU, and the F1s are daunted when Hanssen leaves them alone to face their first New Year’s night shift. Will they sink or swim?

E33 - Episode 33

Aired: January 12, 2021

Skylar’s mistake has fatal consequences, but is she really the one to blame? Kian admits his addiction to Jac, and Donna tries to put Xavier's memory to rest.

E34 - Episode 34

Aired: January 19, 2021

It’s the day of the hearing, but who will the panel listen to, Cameron or Skylar? Jac can’t shake her worries about what Kian is getting up to.

E35 - Episode 35

Aired: January 26, 2021

A returning patient wreaks havoc for Jac, and Sacha fears for his daughter while Jodie is on the loose.

E36 - Episode 36

Aired: February 02, 2021

The hospital is locked down with a gunman on the loose. Trapped in theatre, Cameron needs Nicky's help if he is not to be exposed as being way out of his depth.

E37 - Episode 37

Aired: February 10, 2021

Sacha gets the shock of his life when Jodie appears back on the scene. On her first day on Darwin, Jac's replacement, Sahira Shah, doesn't take kindly to Kian. And a bubbly new nurse, Kylie, arrives in acute admissions, but will she survive her first day?

E38 - Episode 38

Aired: February 16, 2021

Sacha and Hanssen battle to save Dom’s life in theatre, while Jodie is terrified that she might lose her baby. Sahira tries to steady the good ship Holby, up on Darwin.

E39 - Episode 39

Aired: February 23, 2021

Ange blocks Dom's discharge, Alex makes a shocking discovery when a patient arouses his suspicions, and Nicky's health issues return.

E40 - Episode 40

Aired: March 02, 2021

Hanssen is shaken when a figure from his past appears. Cameron is backed into a corner when Bobby arrives on the ward threatening to talk. Ange and Dom clash over his decision to sue the hospital.

E41 - Episode 41

Aired: March 09, 2021

Chloe tells Ange that she thinks Cameron was involved in a patient’s death. Hansen tries to protect Sahira. Will Max ask Lucky to stay, when she proves her worth on her last day?

E42 - Episode 42

Aired: March 16, 2021

After learning from Sahira that he may not have been Reyhan's only victim, a distracted Hanssen makes a terrible mistake in theatre. Will it be life-ending for Reyhan?

E43 - Episode 43

Aired: March 23, 2021

Cameron holds Ange hostage as the truth of his crimes comes to light. Max needs to look out for Louis, but is she up to it? And Dom is back on the ward for the first time since he decided to sue the hospital.

E44 - Episode 44

Aired: March 30, 2021

Reyhan challenges Hanssen to tell Sahira the truth, Nicky vents her frustrations on a shady patient, and the team rally to support Ange after her ordeal with Cameron.