E1 - Kansas

Aired: August 18, 2012

Zoe's first day as the ED'S clinical lead gets off to a trying start when the team are faced with dealing with the aftermath of a tunnel collapse at a music festival.

E2 - Cuckoo's Nest

Aired: August 25, 2012

Tamsin faces a ghost from her past when she and Jeff attend a call out at a lap dancing club. Sam attempts to unravel the mystery of a patient with amnesia.

E3 - Rock, Paper, Scissors

Aired: September 01, 2012

Sam and Tom are pushed to their limits when a female cage fighter insists on fighting against their advice, and a wedding is threatened to be ruined by devastating news.

E4 - An Amateur Sport

Aired: September 15, 2012

Dylan and Tess must treat an agitated pregnant woman, while Fletch tries to unravel the relationship between a teenage girl and her swimming coach.

E5 - I'll See You in My Dreams

Aired: September 22, 2012

The team is put to the test when Holby is hit by severe weather, and the stress of work and dealing with a face from the past leads Big Mac's health to take a dangerous turn.

E6 - Evolve or Be Extinct

Aired: September 29, 2012

Medical drama. Fletch plays a practical joke on Lloyd after a staff night out, and Dylan attempts to teach a medical student about the dangers of alcohol abuse.

E7 - Tough Love

Aired: October 06, 2012

The team deal with an accident at a troubled small business, and a young businessman with heart problems is demanding staff find his missing phone

E8 - The Kindness of Strangers

Aired: October 13, 2012

Zoe oversteps the line when she attempts to help a vulnerable young woman, and Mac gets into serious trouble on his first day back when a patient with Alzheimer's appears to have swallowed some cleaning fluid.

E9 - Harvest Festival (1)

Aired: October 20, 2012

Zoe struggles to deal with the fallout of a suspected E. coli outbreak, and Dylan is touched by an elderly patient who has lost his beloved wife.

E10 - Seeing in the Dark (2)

Aired: October 27, 2012

Zoe and the ED reap the fallout from the E-coli outbreak and things go from bad to worse for farmer Rob.

E11 - When Love Breaks Down

Aired: November 03, 2012

Dylan deals with a woman whose pregnancy is not all it seems, and teenager Angel is desperate to get some cash together to pay off her bullies.

E12 - Out of the Blue

Aired: November 17, 2012

Tamzin's decision not to treat an aggressive patient has serious repercussions, and Tom and Sam differ over how to approach a family with a dark secret.

E13 - Sixteen Candles

Aired: November 24, 2012

A family are shocked to find out an intruder isn't all he seems to be, and a woman finds out she's the heir to her nasty aunt's fortune.

E14 - My Aim Is True

Aired: December 01, 2012

As Charlie and Big Mac prepare for the ED party, Dylan's suspicions reach boiling point.

E15 - The Blame Game

Aired: December 08, 2012

A secret puts a strain on Jeff and Tamzin's friendship and makes life difficult for Dixie.

E16 - I Saw Mommy Killing Santa Claus

Aired: December 15, 2012

Tensions once again rise between Tom and Dominic as they argue over the treatment of a baby with severe hypothermia, and Dylan finally admits that he has not moved on from Sam.

E17 - Rabbits in Headlights

Aired: January 05, 2013

Four student nurses receive a baptism of fire on their first shift in the ED.

E18 - Smoke and Mirrors

Aired: January 12, 2013

Zoe is concerned that Jordan is not facing up to the severity of Yvonne's condition.

E19 - No Other Medicine

Aired: January 19, 2013

Jordan fights to keep his girlfriend's life support machine switched on but when an ill young woman arrives in the ED, he's forced to reconsider his motives.

E20 - Broken Heart Syndrome

Aired: January 26, 2013

It is the day of Yvonne Rippon's funeral, and Nylon gets Jordan to visit him.

E21 - Life Goes On

Aired: February 02, 2013

Jordan is called on to save the life of the person who killed his girlfriend.

E22 - If Not for You

Aired: February 09, 2013

New doctor Ash hits the ground running when he treats a patient with suspected rabies, and Aoife is forced to take control when ex-boyfriend Craig arrives in Holby.

E23 - Ostrich Syndrome

Aired: February 16, 2013

David tracks down his estranged wife, Kate, to get her help in saving their 10-year-old son who is dying of leukaemia. Meanwhile, Zoe has had to go home sick, leaving Ash to deal with the continuing flu epidemic.

E24 - Though Lovers Be Lost

Aired: February 23, 2013

Jeff must persuade David to act in his son's best interests, Fletch is determined to help an elderly man in love, and Zoe returns from sick leave and clashes with Ash.

E25 - Brave New World

Aired: March 02, 2013

Big Mac thinks he may have finally found the woman of his dreams but when she mistakes him for a doctor he doesn't set her straight. Ash clashes with Zoe when he carries out a risky procedure without telling her.

E26 - Cross Roads

Aired: March 09, 2013

Ash and Zoe struggle to make a teenage boy accept the severity of his father's condition, while Linda helps a pregnant woman cope with her waster boyfriend.

E27 - With and Without You

Aired: March 16, 2013

Jeff is caught up in a marital dispute, and Robyn breaches patient confidentiality.

E28 - And the Walls Come Tumbling Down

Aired: March 23, 2013

Robyn has to try and save her friend's life when a day at the fairground goes badly wrong.

E29 - Punch Drunk Love

Aired: March 30, 2013

Tom helps a young man with a troubled home life. Jamie treats a young boxer.

E30 - Hidden (1)

Aired: April 06, 2013

Zoe and Ash must work together to reunite two schoolgirls injured during a science exam.

E31 - Unsilenced (2)

Aired: April 13, 2013

Zoe goes out of her way to help and protect a young girl who she believes is at risk of female genital mutilation. Fletch deals with a man who needs to take responsibility for his health and lifestyle.

E32 - Family Matters

Aired: April 20, 2013

Jeff is distressed when his father and sister are involved in a car accident.

E33 - Human Resources

Aired: April 27, 2013

When hoodies raid an off-licence, a family must pull together to stop the gang's reign.

E34 - The Morning After

Aired: May 04, 2013

Ash deals with his daughter's admission to the ED after being hit by a drunken police driver, while Tom's judgement is called into question when a baby he has discharged nearly dies.

E35 - Isolated Incident

Aired: May 11, 2013

Linda's nursing experience enables her to see the bigger picture concerning a patient.

E36 - The Milk of Human Kindness

Aired: May 25, 2013

Tom is determined to show that a previous misdiagnosis isn't affecting his confidence.

E37 - Love Is the Drug

Aired: June 01, 2013

When Tess witnesses a stabbing she becomes involved with the attacker and victim.

E38 - You Always Hurt the One You Love

Aired: June 08, 2013

Lloyd tries to uncover the truth about a cannabis factory on his final day as a nurse.

E39 - Garage Flowers

Aired: June 15, 2013

Tom faces a dilemma of truth and confidentiality over the paternity of a baby.

E40 - What Goes Up

Aired: June 22, 2013

Ash and Zoe have to protect a local shopkeeper who has been harassed by unruly kids.

E41 - Letting Go

Aired: June 29, 2013

Tom and Sam clash over the best course of action when a mother can no longer cope.

E42 - A History of Violence

Aired: July 06, 2013

When Marcus is mugged, Sam and Fletch work together to reveal who the real victim is.

E43 - Secrets and Lies (1)

Aired: July 13, 2013

Tom is on a personal visit to a prison when unrest breaks out and trouble ensues.

E44 - Mistakes Happen (2)

Aired: July 20, 2013

Arthur and Chantelle struggle to cope in the aftermath of the mugging.